About the Investigational Drug
Tyrosine Kinase Inhibitors (TKIs) like the investigational drug repotrectinib are targeted therapies that attack cancer cells.
Repotrectinib comes in pill or liquid form and is taken by mouth.
HOW CAN I LEARN MORE ABOUT THE CARE STUDY?
If you are located in the United States and interested in learning more about the CARE Study, please complete the following questionnaire and a study representative will contact you within 2-3 business days. You can also contact us directly at (855) 613-3355 (M-F from 8am to 8pm EST). If you are under 18 years of age, please ask your parent or guardian to complete the questionnaire below and contact us directly for further information at (855) 613-3355 (M-F from 8am to 8pm EST).
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Frequently Asked Questions
What is a clinical study?
A clinical study is a type of research study designed to evaluate whether an investigational drug is safe and effective for use in humans. Participants are given specific investigational treatments and researchers closely monitor the results to help determine if the drug should be approved for wider use. The U.S. Food and Drug Administration (FDA) has strict rules that govern how clinical studies are conducted, and requires that an investigational drug be proven safe and effective before it can be widely used in the United States.
What is an investigational drug?
An investigational drug is a drug that has not been approved by the U.S. Food and Drug Administration (FDA) but can be administered to people in a clinical study for research purposes.
What type of clinical study is the CARE Study?
The CARE Study is a phase 1/2 clinical study evaluating an investigational drug, repotrectinib, for the treatment of children and young adults (under age 25) with advanced or solid tumors, primary CNS tumors, or anaplastic large cell lymphoma (ALCL) with ALK+, ROS1+, or NTRK+ alterations. There is no cost to participate in the study and there is no maximum duration for this study. Participants can continue with cycles of treatment until any of the following occur: you/your loved one’s disease worsens, you decide that you/your loved one will no longer participate in the study, the study doctor decides you/your loved one should no longer participate in the study, the study sponsor decides to stop the study.
Study Site Locations
Current U.S. study locations are listed below, and more may be added as they open. If you or a loved one is interested in participating in the CARE Study complete the form to speak with a study representative who can also provide available study locations.